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The statement is true because CBRNE incidents—referring to chemical, biological, radiological, nuclear, and explosive situations—often present a complex and hazardous environment. In such incidents, resources can become overwhelmed due to the scale and severity of the emergency. This can lead to challenges in response efforts, as emergency responders may have difficulty accessing the scene or managing the incident effectively with the personnel and equipment available to them.

Toxic materials are also a critical concern in CBRNE situations, as exposure to hazardous chemicals, biological agents, or radioactive substances can pose significant risks to public health and safety. Finally, the presence of secondary explosive devices is another potential risk factor at these incidents. Perpetrators may set up additional explosives to target responding personnel or hinder rescue efforts, which exacerbates the danger and complexity of the situation.

Therefore, the inclusion of overwhelmed resources, toxic materials, and secondary explosive devices accurately characterizes the types of conditions that can be encountered at a CBRNE incident.